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Controversial NIH Chelation Trial Published In JAMA

Final results of the troubled NIH-sponsored TACT trial testing chelation therapy for coronary disease have now been published in JAMA. Last November, when the preliminary results were presented at the...

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A Guide To The Raging Debate Over The NIH’s TACT Chelation Trial

(Updated) The publication in JAMA of the NIH’s Trial To Assess Chelation Therapy (TACT) trial has provoked a fascinating debate in the blogosphere. The vast majority of responsible physicians and...

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Study Suggests Benefit For Beta Blockers During Noncardiac Surgery

The use of perioperative beta-blockade for noncardiac surgery has been declining as a result of the controversial POISE study, which turned up evidence for harm associated with extended-release...

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Study Questions Role Of Dual-Chamber ICDs For Primary Prevention

Dual-chamber ICDs are implanted in a majority of primary prevention patients without a pacing indication who receive an ICD. Although there are a number of theoretical advantages with dual-chamber...

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Observational Study Lends Support to CRT Guidelines

A large observational study published in JAMA suggests that patients with left bundle-branch block (LBBB) and longer QRS duration derive the most benefit from a cardiac resynchronization therapy...

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Kaiser Program Yields Big Improvements In Hypertension Control

A large percentage of the 65 million people with high blood pressure in the United States do not know they have hypertension or have not succeeded in controlling their hypertension. Although many...

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Study Supports Loosening Guidelines for Surgery After Stent Implantation

According to current guidelines, noncardiac surgery should be delayed for six weeks after bare-metal stent (BMS) implantation and for one year after drug-eluting stent (DES) implantation, though there...

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New Insights Into Surgery Versus Stents For Diabetics With Multivessel Disease

Last year the large NHLBI FREEDOM trial demonstrated that bypass surgery was superior to PCI when treating diabetic patients who have multivessel coronary disease. CABG resulted in significant...

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Flu Vaccine May Help Prevent Cardiovascular Events

A new meta-analysis published in JAMA offers the best evidence yet that the flu vaccine may help prevent cardiovascular events. Jacob  Udell and colleagues analyzed data from 5 published clinical...

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Prolonged Dual Antiplatelet Therapy May Not Be Necessary For...

The precise duration of dual antiplatelet therapy (DAPT) following implantation of a drug-eluting stent (DES) has been the subject of considerable controversy. On the one hand, prolonged therapy may...

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Behind The Curtain: Study Reveals Big Role of Medical Communication Companies

Everyone knows that medical information flows out of medical centers and schools, research institutions and the NIH, pharmaceutical companies, journals and medical societies. But one important...

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Missing High Blood Pressure Guideline Turns Up In JAMA

After  years of delay and many twists and turns, the hypertension guideline originally commissioned by the NIH has now finally been published in JAMA. The evidence-based document contains a major...

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The Expanding Universe: JAMA Announces New Cardiology Journal

Warning: snark and cynicism ahead. I’ve said it before and I’ll say it again: what the world needs now is another cardiology journal. And so, as if they were reading my mind and the collective mind of...

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